| || 關於an overview of all grenades，參見Hand grenades。|
關於an overview of other fragmentation grenades，參見Fragmentation grenades。
關於the grenade from Fallout 2，參見Holy Hand Grenade。
Wild Wasteland的特征，在探照燈營地的教堂地下室捡到，guarded by two golden geckos.Players without the trait will find two mini nukes in the location instead. If the player originally did not choose the Wild Wasteland trait, but switched to it using the Auto-Doc in Old World Blues before taking the mini nukes, then the Holy Frag Grenades can still be obtained.整个游戏就3个，选了
- Characters with Loose Cannon may be unable to escape the blast, even if thrown the furthest possible distance. This becomes particularly problematic when combined with Splash Damage.
- When thrown, the grenade no longer has the white cross on it and looks like a normal frag grenade.
- Due to the grenade's high damage, if you are not killed in the blast, your armor may break or become so damaged its DT is negligible.
- The blast radius will surely turn any passive creature that survives the blast hostile, even with the Animal Friend perk. This can be used to the player's advantage to flush out enemies at long range to clear fast travel restrictions.
- Despite being a unique, more powerful version of frag grenade, Holy Frag Grenades are not considered a holdout weapon
- When taking into account reload times, it has the highest DPS of any explosive weapon.
Behind the scenes编辑
- The Holy Frag Grenade is a reference to the "Holy Hand Grenade of Antioch" which was featured in cult comedy film Monty Python and the Holy Grail. The writing on the box next to the grenades is also a reference to a line in the film.
- The Holy Hand Grenade also appeared in Fallout 2, with a special encounter built around the grenade and further references to the film.
- If dropped, the Holy Frag Grenade may be stuck where it is dropped. While they can be picked back up, the player cannot freely position them for display. [已核实]
- In the first seconds after loading the game and the Courier had the Holy Frag Grenade equipped, the blast of the Holy Frag Grenade may not do any damage to the Courier, followers or NPCs, but there will be radiation on the place where the Holy Frag Grenade exploded. Damage from hitting the person will also be taken in account. [已核实]