|關於an overview of plasma pistol variants in the Fallout series of games，參見plasma pistol。|
關於the Gun Runners' Arsenal version of this weapon，參見Plasma Defender (GRA)。
The Plasma Defender is a powerful energy-based pistol which fires superheated bolts of green plasma. It is able to punch through most critters and low-level armor with ease, when compared to the more commonly found and cheaper laser pistol.
In comparison to the standard laser pistol, the Plasma Defender deals more than 3 times the damage per shot and over twice as much damage-per-second (DPS). This is offset by the fact that it consumes energy cells at twice the rate, has reduced durability, and has a slightly increased spread. Additionally, it causes a large green burst of plasma upon firing which in addition to partially obscuring the view, travels at a slower rate, resulting in the need to lead the target.
In comparison to the plasma pistol, the plasma defender does an additional 5 damage per shot, has a reduced critical chance, and is less durable. However, the plasma defender is a more accurate weapon, uses fewer Action Points in V.A.T.S. and has a higher rate of fire in real-time, delivering almost twice as much DPS. Unlike the plasma pistol, the plasma defender is not considered a holdout weapon.
- Arcade's Plasma Defender is a unique non-playable Plasma Defender used by Arcade Gannon. It only differs from the standard pistol in its use of companion ammunition.
- Plasma Defender (GRA), a variant that can accept modifications.
- Lucky 38, in a floor safe of the cocktail lounge.
- Silver Rush, located on a table and sold by Gloria Van Graff.
- Dead Bright Brotherhood followers have a 1-in-3 chance of carrying Plasma Defender once the Courier has reached Level 8. They can be found at REPCONN test site along with other energy weapons.
- Y-17 trauma override harness may carry them on higher levels.
- Hopeville silo bunker entrance, located in a desk with a Hard lock.
- marked men. Spawns as a random weapon on
- Plasma Defenders are not randomly sold by any merchants, including the Van Graffs and the Gun Runners. This is due to their absence from a number of leveled item lists, while being present on several other lists which are not used. The only exception is a single Plasma Defender which can be found on the display table in front of Gloria Van Graff.
The Plasma Defender is meant to closely resemble the "Glock 86" Plasma pistol from Fallout 1 and 2, especially when all of the modifications are added.