The Bobblehead - Medicine permanently increases your Medicine skill by 10 points. Items such as The Surgeon's Lab Coat or Winterized Medic Armor can temporarily raise it. You can read D.C. Journal of Internal Medicine to raise Medicine skill as well.
- 30 Medicine is required to properly examine the bodies of the West family for the Blood Ties quest in Arefu.
- 40 Medicine is required to revive Timebomb in Bigtown, which is the only way to get his Lucky 8 Ball.
- 50 Medicine is required to help a slave in The Mill inside The Pitt, although there is no reward for doing so.
- 60 Medicine is required to revive Reilly in the Chop Shop in Underworld, which is one of two ways to revive her and start the Reilly's Rangers (quest).
In certain cases having an average-high Medicine skill can give you extra dialog option, such as talking to Doc Church of Megaton or speaking to Reilly of Reilly's Rangers after you resurrect her from her coma, saying she should relax for her health's best interest.