The town of Clarksburg has many buildings along its central street, including a supermarket/pharmacy, a post office, a church, ice cream parlor, a gun store with an armory that can be unlocked via a level 2 terminal, a hardware store, and a couple of decimated houses on the outskirts of town. The Clarksburg Shooting Club can also be found here.
- Raider power armor - Located on the fourth floor of the brick building on the east end of town. Accessed via the fire escape by taking the stairs behind the gun shop to the roof.
- Fusion core - In the basement of the warehouse on the western end of town.
- 機密安全資料和重要備忘錄 - 懸案任務期間於郵局內的郵箱取得。
- 瑪麗的日記頁 - 野餐驚魂任務期間於鎮上西北部半沉的拖車屋取得，在背包裡。
- Chainsaw - Can spawn on a shelf inside the hardware store at the top balcony.
雀爾西的日記頁 - 無法被撿起的筆記, in a house on the eastern side of town.
Clarksburg appears only in Fallout 76.