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Zeke may refer to:
- Zeke (Fallout 2), a squatter at Vault 15 in Fallout 2.
- Zeke (Fallout 4), the founder of the Atom Cats in Fallout 4.
- Zeke (Fallout 76), a Mister Handy at Camden Park in Fallout 76.
- MTR04 Zeke.txt, dialogue for Zeke in Fallout 76.
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