The Vault 81 cure is a consumable item in Fallout 4.


The Vault 81 cure is the only cure for the mole rat disease contracted after being bitten by a Vault 81 lab mole rat. There is only one dose given to the player character by Curie and one has to decide if they want to give it to Austin or keep it for themselves in the case they have contracted the disease.


It is given to the player character by Curie once they allow her to open the door.

Related quest


  • If a companion gets bitten, then the Sole Survivor will become infected. The best way to avoid contracting the disease is to go in alone and use rapid-firing weapons in order to kill the mole rats quickly.
  • In Survival mode, using the cure on one's self will instantly make them severely dehydrated, regardless of their hydration levels beforehand.
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