Upon the Brotherhood'sScourge of the Pitt, Uptown, like the rest of the city, was completely lawless and inhabited by raider gangs. However, since Ishmael Ashur took control of the city and assimilated or killed all of the raiders, Uptown has become The Pitt's "Upper class" district. Under Ashur's new rule, anyone of importance to the city such as traders, scientists, and Pitt raiders have relocated to Uptown where they live superior to the slaves of downtown. Uptown is where Ashur resides in Haven, as well as his army.
Most of the bottom section of Uptown is irradiated. Above is where the Pitt raiders live. They have their own rooms and large numbers of chems and alcohol that can be stolen.