This is the first in a series of eight quests which leads to one of the many Fallout: New Vegas endings. Mr. House tasks the Courier with retrieving the platinum chip from Benny and using it at the Fort to activate the securitron army below, then bring it back to the Lucky 38 so that Mr. House can upgrade them.
For part two of the quest, the Courier must travel to Cottonwood Cove and take a raft to the Fort, where Mr. House's secure bunker is located. If one has already collected the platinum chip, Mr. House will return it to them; if not, the player character will need to get it back from Benny when they get there.
Mr. House asks the player character to deal with the Omertas for him. The player character can achieve this by completing the side quest How Little We Know or killing all the Omertas. Upon doing either, the player character must then return to Mr. House.
Protect President Kimball from an assassination attempt on Hoover Dam. Follow Ranger Grant to the observation deck, then tell the Ranger that they are ready and a vertibird will land above the player character.
The player character must install the override module at the El Dorado substation. Several NCR troops guard the substation and warn the player character that there will be trouble if they enter.
There is a quest named The House Always Wins (without number) in the G.E.C.K. While unused, it appears to be simply all of Mr. House's main quests combined into one, from meeting him for the first time at the Lucky 38 to defeating Caesar's Legion at Hoover Dam.
"The house always wins" is a popular saying describing how casino games have an inherent bias toward the casino, or "house" (described as the "house edge") so that in the long run the casino will nearly always come out ahead.