When injected, a super stimpak heals 75 HP immediately, but the powerful nature of drugs used in the process will cause an adverse reaction from the organism, resulting in draining 9 HP after two minutes.
The super stimpak is a rare sight in the wasteland, usually only available from high tech settlements, such as Vault City or San Francisco.
Occasionally, a chemistry genius has been known to whip up a "super stimpak." A player character who is medically-inclined ( i.e.: 76% Doctor skill or more ) or Myron can create one from the following recipe: One stimpak, one Nuka-Cola and one fruit.
Five are found inside of an ice chest located in the room where Dr. Wu is located in The Cathedral's interior. This ice chest is locked, however, and must be lock picked in order to open it. In the higher levels of The Cathedral, Morpheus possesses one super stimpak.