Before the Great War, South Boston was a neighborhood serviced by Andrew station and patrolled by the Boston Police Department from the South Boston precinct. The district was industrial, containing several factories and plants. It was also the primary area of operation for a notorious crime boss, Eddie Winter. Molly, a raider living in Appalachia, describes the district before the war, explaining that it was "real bad" with "military blockades, trigger-happy cops, and looming over it all, the monster himself. Eddie. Winter."
One of the oldest buildings in the area is The Castle, formerly known as Fort Independence, which predated the American Revolutionary War. After the bombs fell, the Commonwealth Minutemen adopted the Castle as their headquarters, before being driven out by mirelurks in 2240. Marowski, a post-War drug kingpin, also operates a chem lab in the Four Leaf fishpacking plant. The area is now home to bands of raiders, super mutants, and mirelurks.
- Andrew station
- Bus and apartment wreckage
- Dorchester Height monument
- Four Leaf fishpacking plant
- General Atomics factory
- Gwinnett Brewery
- Hawthorne Estate
- Joe's Spuckies sandwich shop
- L Street bathhouse
- South Boston Church
- South Boston High School
- South Boston military checkpoint
- South Boston Police Department
- The Castle
- The Gwinnett Restaurant
- Union Man's Circle
- Boston Bugle building terminal entries; Boston Bugle Article terminal, Article 1
- Vault Dweller: "Pouring drinks for bandits seems like a fast way to get yourself killed. You aren't worried for your own safety?"
Molly: "Worried? Pfft. Hardly. Sure, I lock my cap stash up at night, but these folks are pussycats compared to the ones I grew up around. South Boston, before the bombs, real bad. Military blockades, trigger-happy cops, and looming over it all, the monster himself. Eddie. Winter. Nah, I'll pour drinks for these troublemakers any day of the week over that life again."
- Fallout 4 Vault Dweller's Survival Guide p. 517: " The Castle
Historians have noted the original name for this settlement was Fort Independence,but the people of the Commonwealth now refer to it simply as the Castle. This place has a long and storied history; it is one of the first forts in America and predates the Revolutionary War. In recent times, it served as the base of operations for the Minutemen as they attempted and failed) to establish a Provisional government. In 2240, the Castle was partly destroyed by gigantic Mirelurk, and most of the Minutemen leadership died."