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Rose may refer to:
- Rose (Fallout 2), is Cornelius' wife in Fallout 2.
- Woodrose, the tribe mother of the Point Lookout tribals in the Fallout 3 add-on, Point Lookout.
- Rose of Sharon Cassidy, a possible companion found at the Mojave Outpost in Fallout: New Vegas.
- Rose (Fallout: New Vegas), a prostitute that worked for Joseph B. Steyn mentioned in Fallout: New Vegas.
- Rose (Fallout 76), leader of the raiders in Fallout 76
- Real-life people: