If the bottom speech options are chosen when first talking to her, Reilly gets mad and will never talk to the Lone Wanderer again.
Depending on how she is woken up, Reilly's legs are crippled and can be seen limping if the Medicine skill is used to wake her up. However, she will look like normal if Doctor Barrows' Speech check is used to wake her up.
If asked why there are so many mutants in the area she states that Brick thinks that there is something in the area they're looking for. As later discovered, they are searching for human abductees to expose to the F.E.V., which they use to make more super mutants.
If one has the Gun Nut perk, a Speech option is available to say that the Lone Wanderer has heard of Reilly's Rangers before and that they pack serious firepower. This has no other effect but variance.
If one angers Reilly, she and her rangers will become hostile. If one attacks the rangers, Underworld residents will not become hostile to the Lone Wanderer and will attack Reilly. This also works the other way around, if the player character attacks Underworld residents, Reilly will help them in battle.
Reilly keeps notes of her teammates in her terminal which are written as reports. According to her computer files, she and Butcher are in a complicated relationship, which she worries may jeopardize their professional relationship.
If asked about Talon Company, Reilly will tell about an encounter with them in which Brick, the team's Heavy Weapons specialist, almost fought with a detachment of them. In her report on Brick, Reilly states that Brick nearly massacred them. She also states that Theo, the ranger lost in the Statesman Hotel was a full ranger. His contract is marked in her notes as "probationary."
"I'm very impressed at your skill. I don't think I've come across someone quite like you in the ruins. I suppose I owe you a debt, and I intend to pay it in kind. I'm sure you're more interested in your reward than listening to me talk, so let me get right to it."
"Wow. You sound like one of the guys from Talon Company. Ruthless bastard, aren't you? You can act badass all day, doesn't phase me. You're chicken shit compared to some of the guys I've dealt with.To answer your question, yeah, I got your damn reward. Now, how about that debrief?"
PC Sometimes Reilly, when in Underworld's hospital, gets stuck in a dialogue with no exit options. This seems to occur when you listen to her quest suggestion Reilly's Rangers, choose to think about it, and return later, but the quest already appears on your Pip-Boy and states "Find Reilly in Underworld". Carrying out a quick save before talking to her is recommended. [verified]
PC If you have the Gauss rifle, and you remain hidden, in Underworld's hospital, then shoot Reilly while she is still unconscious, she will fall off the bed and stand up, but you won't be able to talk to her, though you are able to revive her with the required 60 Medicine. [verified]
↑Fallout 3 Official Game Guide p. 432: "18.06 REILLY'S RANGERS COMPOUND": "Growing up in the ruins of Washington D.C. without parents, Reilly encountered a military man who took her in and taught her everything there was to know about combat, tactics and survival . When he died 12 years later, she carried his body all the way to Arlington Cemetery, and gave him the best military burial she could. Four years ago at 26, she founded Reilly's Rangers, and began a massive mapping exercise. Currently, she has suffered severe wounds, and is in a coma, somewhere near the Ghoul stronghold of Underworld. Before she meets the Lone Wanderer, her team was held up near Vernon Square by a large pack of super mutants where she was injured and nearly killed when she attempted to escape. The Lone Wanderer can assist her in her recovery, as well as finding and rescuing her team." (Tour of the Capital Wasteland)