Ascorti, the mayor of Redding, is looking for someone to buy the Great wanamingo mine. The buyer will get twice the price if they get rid of the wanamingos. Doc Johnson can treat the wounded. Also, he is looking for a cure for Jet addiction.
Also, there are rumors he can make implants, as long as they have a suit of combat armor and caps. The sheriff, Earl Marion, is looking for a trustworthy person to take care of some jobs, like stopping a brawl in Malamute Saloon, tracking down a person who cut Malamute Sallon's prostitute and even killing Frog Morton.
Redding Downtown appears only in Fallout 2.