When under the effects of Advanced Radiation Poisoning (400+ Rads) any crippled limbs will automatically regenerate. This perk is gained by getting exposed to Critical Radiation Poisoning (600+ rads) for Moira's Wasteland Survival Guide. This mutation is a result of Moira's experimental radiation treatment.
- Advanced Rad Poisoning causes a loss of two points of Endurance and one point of Agility. This equates to a temporary skill reduction of four to Big Guns and Unarmed, as well as two to Small Guns, Sneak, and total Action Points.
- Adamantium Skeleton is better at protecting limbs from crippling injury, yet it carries no penalties. However, Rad Regeneration is easier to get, and having the regeneration active means that a limb will start healing as soon as it gets crippled, and even having a single point of 'limb health' means that the limb is no longer crippled.
- The perk still exists in the game files of Fallout: New Vegas, albeit only as legacy content.