Paige is first encountered in the quest Here to Stay, after the Vault 76 overseer asks the Vault 76 residents to warn him of the threat of the Scorched Plague to the Settlers and have them inoculated with the vaccine. Paige is initially hesitant to trust the residents and asks that they meet with Aubrie Willem and tell him of the threat. If Aubrie agrees to the vaccine, then Paige will support it as well. Once Aubrie is found and told of the threat and has it passed back to Paige, he will agree to have his Settlers inoculated. He is a little surprised later to find the vaccine comes as a new flavor of Nuka-Cola, but nonetheless expresses gratitude to the residents for protecting his Settlers from the Scorched and Scorchbeasts.
Paige can be chosen over Meg and her raiders for a raid on Vault 79 after telling him of the Vault being where the United States' gold bullion reserves have been stored and how it could help rebuild Appalachia's economy.