There are four distinct types of houses in the town, aside from those which have been completely destroyed. Most have the basic facilities, such as seating, bedroom, a kitchen, workspaces, and bathrooms. One of the houses is occupied by a hostile Mister Gutsy prototype, while another one is booby-trapped with caged bark scorpions in the first room, and tripwire-activated single shotguns at the doorways.
- Sunset Sarsaparilla star bottle cap - On top of the bookshelf in the bedroom, in the house in front of the Nipton General Store.
- Declaration of Vital Essence - A paper note, in the booby-trapped house.
The smaller, white houses are not rectangular in the inside as the outside of the building would suggest.
The Nipton houses appear only in Fallout: New Vegas.