The area consists of the Nipton Road general store, a destroyed house to the south, and an inaccessible house to the north. The area is infested with several radscorpions of various sizes. In front of the store is a large, destroyed vehicle containing two ammunition boxes. There are no enemies inside the general store, but the player character will find Mayor Steyn's "secret stash," consisting of several sacks and a locked gun cabinet, as mentioned on the terminal in his office in Nipton Hall.
- A Pugilism Illustrated skill book - On the wooden shelf closest to the cash register.
- A Sunset Sarsaparilla star bottle cap - Between the regular caps on the counter behind the cash register.
- Mayor Steyn's journal 2/2 - On the counter between the wall and the cash register.
- Outside, there is a garage with the text "Where's New Canaan, anyway?" The text refers to the city of New Canaan mentioned in the Fallout: New Vegas add-on Honest Hearts.
- The general store has graffiti above the awning, including the name "Lester." This graffiti is also seen in Vault 3.
- A dead Bright follower can be found lying against the gas station sign.
- The Nipton Road general store at this location is different from the Nipton General Store, located within the town of Nipton. The store within the town of Nipton is colloquially known as the "Nipton Trading Post."
The Nipton Road reststop appears only in Fallout: New Vegas.