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Natalie may refer to:
- Natalia Dubrovhsky, a resident of Vault 13 and one of the pre-made possible identities of the Vault Dweller in Fallout.
- Natalie "Nat" Wright, the sister of Piper Wright and a resident of Diamond City in Fallout 4.
- Natalie (Quincy), a survivor of the Quincy Massacre, mentioned in Fallout 4.
- Natalie Ingesson, a researcher for Arktos Pharma, mentioned in Fallout 76.
- Natalie (Fallout 76), a member of the Free States, mentioned in Fallout 76.
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