After the Lone Wanderer has completed The Nuka-Cola Challenge and Mississippi Quantum Pie quests for Sierra Petrovita, she can make Mississippi Quantum pie if they ask her about recipes. Its effects are basically those of a Nuka-Cola Quantum and vodka combined, without the Charisma boost or the chance of addiction.
- Flour, a miscellaneous item, is rare to find in the wasteland.
- Compared to Quantum itself, the only added negative effect is a 1-point reduction in Intelligence, which is offset by the Strength bonus and removed risk of addiction.
- Mississippi Quantum pies are valued at less than half the combined price of their ingredients: 20 caps value versus a combined value of 52 caps (Nuka-Cola Quantum - 30, vodka - 20, flour - 2).