Simms was born in 2236. He grew up in Megaton and understands what it takes to survive and thrive in the wasteland. Big and imposing yet warm and friendly, Lucas won his position by a unanimous vote of the people of Megaton (most of whom genuinely love the guy). He serves as mayor, sheriff, judge, and just about any other position that's needed. It's also no secret around Megaton that he is fulfilling a childhood cowboy fantasy after his father read him stories as a child. He named his son Harden after the Old West outlaw John Wesley Harden. Simms is also a member of a secret society known only as "the Regulators."
He often contests the title of "mayor" with Colin Moriarty. While Moriarty claims Megaton to be "his city," Megaton's other citizens agree that Simms is the real mayor. Simms, who despises Moriarty, warns the player of talking to Moriarty and tells the same to his son.
If the Lone Wanderer chooses to tell Lucas about Burke's plot, it is possible for them to save Simms by killing Burke before he gets to shoot Simms. This also spawns a dialogue choice of Lucas commenting on how he "must be getting slow," and he will thank the player character for saving his life.
If the Lone Wanderer chooses to tell him about their plan of detonating the bomb, he will turn hostile along with every other Megaton settler.
If the player character chooses not to save him and then kills Burke, the player character receives positive Karma and has the option of looting both of their bodies with no additional negative Karma. They can then receive the reward for disarming the bomb from Lucas's son, Harden.
When Mister Burke kills Lucas, a floating blood splatter can sometimes be found walking the same path that he once did. It can cause the game to freeze and you will need to restart the console. [verified]
Rarely, even though you kill Burke before he kills Lucas, the latter may still die. He will simply walk out of the saloon and collapse.[verified]
On rare occasions, Lucas Simms may follow you out of Megaton and stay behind you regardless of where you travel to. However, he is not hostile, although his health bar does show and he is wielding his gun.[verified]