|For the Fallout: New Vegas add-on of the same name, see Lonesome Road (add-on).|
When you have no companions, this perk grants a 10% increase in both the damage done by the Courier and your chance to hit in V.A.T.S. To use this perk, companions must be dismissed; telling them to wait will not grant the perk's bonuses.
This perk cannot be obtained if the quest The End is completed.
Behind the scenes
The representation of the Lonesome Road perk is a reference to the Vault Dweller ending in Fallout, the Lone Wanderer ending in Fallout 3 and the Courier ending in Fallout: New Vegas, where the three are shown walking away, with their back turned and showing the number of the Vault jumpsuit they wear. In the Fallout 3 ending, the Lone Wanderer is shown with Dogmeat, while in Fallout and Fallout: New Vegas, the character is shown alone.
This perk is not always given to the player, and you either have to delete the patch for the game and download it again, or delete Lonesome Road and download that again. [verified]