- If having left the farm, it's impossible to return there, even if not all the raiders are killed.
- The Vault Dweller must be at least Level 5 to get to this place.
- If accompanied by companions, they tend to rush into the house upon the beginning of combat, only to be surrounded by raiders in no time. Their quick demise can be prevented by going to the west corner of the map and dismissing them there. As there is only one entrance to the farmstead, open the door, and position the player character inside the doorframe to block the passage. Initiate combat and the teammates will come to help, despite them being dismissed. They can just be re-recruited after the fight.
- Just outside the farmstead lies the skeleton of what appears to be Irwin's donkey, Pugsley.
Irwin's Farm appears only in Fallout.
Savegames here name the location as "Error."