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Institute BioScience is a section of The Institute in 2287.


The Bioscience division specializes in botany, genetics, and medicine, and is the primary supplier of water and edible foodstuffs for the Institute. It cultivates highly specialized breeds of flora for use in food and medicine, and has started experimenting with creating synthetic animals, such as gorillas. Isaac Karlin, who gives the quest Building a Better Crop, and Clayton Holdren, who gives the quest Hypothesis, are here. The division's head is Clayton Holdren.[1]


The BioScience area consists of a large central lab with a series of connected adjacent work areas and storerooms, as well as two entrances to the Institute FEV lab: a Master-locked terminal to deactivate a laser grid on the north side of the central lab, and a Novice-locked door in the back hallways to the east.


Notable loot


The gorillas may be teleported along to assist in the fight against the Brotherhood during the quest Airship Down.


Institute BioScience appears only in Fallout 4.



  1. Clayton Holdren: "Welcome! So good to have you here. Doctor Clayton Holdren, head of the BioScience division. I can't wait for you to see the work we're doing. It's truly amazing."
    The Sole Survivor: "I look forward to learning more about it."
    Clayton Holdren: "In that case, let me give you a brief overview of what we do here. As the name implies, the BioScience division specializes in fields of study such as botany, genetics and medicine. Our most important directive is to ensure the health and well-being of everyone in the Institute. To that end, we cultivate highly specialized breeds of flora for use in food and medicine. We've even started to explore the idea of synthetic animal life. You probably saw the gorillas... they're really just a pet project at this point, but the potential is exciting nonetheless."
    (Clayton Holdren's dialogue)
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