The Appalachia Super Mutants were created shortly before the Great War, when West Tek contaminated the river water that ran through Huntersville with a strain of FEV as part of an experiment.
The super mutants of Huntersville are similar to those of Mariposa and the Institute: they have green skin, highly developed musculature, and they are smart enough to build improvised armor from waste or scrap. Although they do not use large fortifications like the Vault 87 or the Institute strain super mutants, they can occasionally build small fortresses or take entire buildings. Like Vault 87 and Institute super mutants, Huntersville super mutants can develop into behemoths, which can be seen guarding their main bases.
The majority of the super mutants will attack the player character, but some super mutants like Grahm are friendly and will even trade with humans.
Huntersville super mutants have green skin, hyper-developed musculature and are a slightly larger size than humans. Due to the nature of FEV and its origins as the Pan-Immunity Virion Project, super mutants should be completely immune to the Scorched Plague. However, behemoths are still able to become infected.
They possess great strength, which allows them to inflict serious damage with melee weapons, but strong protection can limit the damage done.
Super mutants are carnivorous and hunt all kinds of creatures and animals, including humans, Scorched and large predators, to devour them or stock their meat to build up reserves. Many bags of meat are strewn about in the fortifications of super mutants or carried in their inventory.
The Huntersville super mutants live mostly in small, well-organized groups, often led by a much stronger super mutant.
They often build armor made from scrap iron or rubbish that can provide some protection against the player character's attacks. These armors include the same ones from Fallout 4 and some new ones the most common of which is a mask fashioned from a propane tank. They attack their opponents most often with rudimentary firearms like pipe pistols or more advanced weapons like rifles, shotguns or even missile launchers. Many super mutants fight with melee weapons or use explosives to attack from a distance.
It's rare to see a super mutant escape during a fight because they are not afraid to attack big predators. This includes deathclaws, mega sloths or Scorchbeasts, and will continue to fight even if they are injured.
A powerful super mutant normally only seen as the boss of the Daily Ops quests. He will usually be armed with an assault rifle with the ability to fire floater flamer grenades, and will occasionally throw Molotovs to burn enemies. His appearance is also different as his skin is observed to be a more red-toned color compared to the normal green of other super mutants. He also has a skull pattern painted onto his face.
A super mutant that will run at its enemy with a beeping mini-nuke in its arm. It will then detonate itself while nearby by slamming the mini nuke into the ground like spiking a football, setting it off, killing its enemy and itself in a fiery, nuclear explosion. Shooting the mini-nuke in the suicider's hand or targeting the right arm in V.A.T.S. will cause the mutant to explode prematurely, killing it instantly. As a result, shooting the bomb from afar is one of the most effective ways to dispatch them, and potentially other nearby enemies as well. If one is desperate to kill a suicider and the only weapon types available are unarmed and/or melee, the player may either sneak attack it, or run-up to it, strike it, step back a bit, and repeat until it's dead (though the latter is not advised as one missed attack will allow the suicider to detonate the mini-nuke, and accidentally hitting the mini-nuke with either type of attack will detonate it). The suicider can be detected before it is seen by listening for the beeping of its mini-nuke. If the suicider is killed without detonating the payload, which can be done with a headshot or body shot, a mini nuke can be looted from its corpse; otherwise, only nuclear material will be found on its remains.
Behemoths are powerful super mutants that have grown to an enormous size. Being the oldest and strongest of their kind, they lack intelligent speech, having to resort to guttural roars to communicate. Behemoths are armed with a fire hydrant still mounted to a massive water pipe. They also can throw heavy boulders from the shopping cart on their back.
↑Fallout 76 loading screens: "The first Super Mutants in Appalachia were created right before the Great War, when West Tek poisoned the drinking water of Huntersville with the FEV Virus, in a sinister, secret experiment gone horribly wrong."
↑Daniel Shin: "Eliminate any Super Mutant you encounter. It remains unclear what's causing them to multiply, so we can't take any risks. Besides that, they are an abomination to humankind, and a threat to civilians across Appalachia. They cannot be allowed to live. Be ready for new orders at a moment's notice. As soon as we put together a more targeted plan for dealing with them, we'll need you at the forefront."[verification needed]
↑The Vault Dweller: "What do you think of the Super Mutants that attacked?" Odessa Valdez: "They're unsettling. They can use human weapons, mount an organized offensive, and they targeted us for an attack. I get the feeling we haven't seen the last of them."[verification needed]
↑The Vault Dweller: "Why are the Super Mutants such a big concern?" Daniel Shin: "One: they're an unknown. I understand these creatures have been sighted around Appalachia for some time now, but this is the Brotherhood's first time dealing with them. We need more information before we can count this threat as controlled. Two: they targeted us directly. The blow they dealt to this base is unacceptable. We must determine their motives, if any, and take appropriate steps to ensure this never happens again. Three: they're an abomination. We've seen all kinds of mutants, but these are... uncannily human. It's an affront to nature to simply let them be."[verification needed]
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