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The Vault 76 overseer wants to make sure that the new arrivals in Appalachia, both the raiders and the settlers, are inoculated against the Scorched Plague. It's up to the residents to see this happen.
The quest is given by the Vault 76 overseer at her home, alongside Strange Bedfellows. The first step is traveling to Foundation at Spruce Knob, and talking to Paige over at Founder's Hall underground. After the player warns him about the danger of the Scorched Plague, he is willing to believe them, but wants Aubrie Willem, the Foundation's co-founder and doctor, to confirm the necessity of inoculation against the Plague.
Aubrie is found at a small camp northwest of Vault 96, but the camp has been overrun by Scorched. After disposing of them, the player has to inspect the dead bodies (Luck 8+ allows the player to search one of the bodies for clues; another can be searched with Perception 8+ to yield two stimpaks and a trail). After examining all four bodies, the player finds a trail that leads north.
The trail of footsteps leads to a secluded cave. Aubrie is found inside. He's spooked and will at first accuse the player of being with the scorched. He can be pacified with Charisma 4+. The player can mention the Plague and the inoculation against it. When Aubrie asks about the specifics of the Plague, Intelligence 4+ allows for quickly summarizing the transmission method, incubation period, and the availability of an inoculation. Once Aubrie's convinced, the player can return to Foundation and report to Paige that Aubrie backed them up and the inoculation is necessary.
Reporting back to Paige completes the quest.
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