Like feral ghouls and other robots in the Commonwealth, the limbs of Mister Handies can fall off or otherwise break when they take damage. This is also true for Mister Gutsies. Codsworth and Curie are immune to this mechanic due to their status as companions. Mister Handies can sometimes spawn in a state of disrepair, with one or more of their limbs or chassis panels missing.
Mister Handies have a variety of weapon configurations, typically utilizing buzzsaws and flamethrowers. Like other robots, if all of a Mister Handy's means of attack are disabled, it will initiate its self destruct and charge its enemy.
The Mister Handy wrecker is a hostile version of the Mister Handy. Usually seen fighting together with Rust Devils this robot can be a dangerous foe if paired with other robots.
Mr Frothy is a unique, Nuka-Cola inspired variant of Mister Handy located in Nuka-World. Its torso is specially altered to be cubic and reminiscent of Nuka-Cola vending machines. Its body is painted red, with the words "Nuka Cola" written on the front of its torso in its usual font. At the end of each of its arms is a red fan, which was used in conjunction with pressurized tanks in Mr Frothy's torso to spray guests with Nuka-Cola before the war. The raiders in Nuka-Town USA can sometimes be heard commenting on this. In 2287, the spray deals direct damage in addition to radiation damage to its targets.
A version of Mr. Handy used by the Gunners. It is frequently found in Gunners bases and outposts. Alongside poison and radiation resistance, the gunner Mr. Handy also has 25 points of frost and fire resistance.
The instructions on the box provide warnings to consumers, such as "Consult your physician before following Mr. Handy's medical advice" and "Mr. Handy's jet is a fire hazard, not a BBQ grill. Use with caution."
A "Mrs. Handy" product texture is found in the game files.
All Mister Handies can wear a bowler hat, including both Codsworth and Curie and all the named Mr. Handies.