Icon disambig
For the condition that lists diseases in Fallout 76, see Fallout 76 diseases.
This page lists all mutations in Fallout 76.
  • The content is not described in full detail on this page. For details, please see the respective articles.
  • For mutations in other Fallout games, please see "Mutation."
  • For an overview of Fallout 76 content, please refer to "Portal:Fallout 76."

General information

Radiation has given you a Mutation! You gain positive and negative effects. Using RadAway has a chance to cure any Mutations.— Notification

Fallout 76 alters the way radiation works: Instead of only limiting SPECIAL stats or max health, it allows the player character to develop various mutations, which act like traits in other games in the series. Mutations are a type of condition that give a mixture of powerful positive and negative effects. The Class Freak perk will reduce the negative effects of a mutation by up to 75%, while Strange in Numbers will grant a 25% increase to the positive effect if teammates are also mutated.

It is also possible to acquire multiple mutations at the same time, including all 19 that are currently available (the sole exception is Carnivore and Herbivore which lock each other from being acquired). However, to have all 19 active is wildly disproportionate to any playstyle and is recommended to pursue mutations that synergize with each other.

A player character wielding a legendary weapon with the "Mutant's" prefix will do 10% more damage when mutated.


Whenever a player takes Radiation damage, they have a chance to gain a Mutation, equivalent to 5% per 5 points of radiation damage (if they are not below level 5). This can occur from being struck by excessive background radiation from a source such as zones devastated by nukes, irradiated creatures, radioactive waste etc. Mutations may also be gained by consuming a mutation serum which allows a specific mutation to be gained.


Serums are consumable items that will grant a specific Mutation as the player uses it, and temporarily suppresses the negative effects of the Mutation and increases the positive effects. If the player already has the mutation, the serum will still temporarily suppress the negative effects of the Mutation but will not stack the positive effects. For example, purchasing a Marsupial serum and consuming it while you already have the Marsupial mutation will remove the intelligence debuff.

All serums and their recipes are sold by the MODUS science terminal at the Whitespring bunker Science Wing terminal. Recipes for the serums can also be purchased from MODUS but have a steep price of 24000 caps per recipe.

Prior to patch, mutation serum recipes also had a chance to be dropped by the scorchbeast queen.

Prevention and Removal

Mutations are semi-permanent. Every time the player uses RadAway or a decontamination shower, there is a chance that a Mutation will be removed. They can keep using RadAway for more attempts to remove a Mutation. Radiation protection gear (e.g. hazmat suit or gas mask) reduces the chance of mutation. The Starched Genes perk allows for locking mutations, as it reduces/eliminates both the chance of becoming mutated and their removal chance by RadAway. These are the only ways present to remove mutations. Mutations cannot be removed through death. However, a percentage of rads is removed through each death, so it's possible to mostly but not completely decontaminate oneself through multiple deaths if the Starched Genes is not yet acquired.


Even with the Starched Genes perk, a Mutations' effects can be suppressed for a time with the use Rad-X. The suppression lasts for approximately 10 minutes (1 hour in-game). To avoid the suppression effects of Rad-X, the diluted version can be used as it offers the benefits of it without the suppression effect.

Available mutations

A player character can be affected by these mutations:

Mutation Positive Effect(s) Negative Effect(s) Percent Chance Base ID
Adrenal Reaction +Weapon DMG at low HP Max HP -50 004e1f14
Bird Bones AGI +4, Fall from heights more gradual STR -4 003c403d
Carnivore No disease from Meat and 2x bonus to Food from eating meat products. Eating fruits, and vegetables does not satisfy hunger. 003c4049
Chameleon Invisibility in combat if unarmored and standing still Must be unarmored, stationary, and not attacking for effect to work 004e4006
Eagle Eyes Critical Damage +25%, PER +4 STR -4 003c4037
Egg Head INT +6 STR -3, END -3 003c4045
Electrically Charged Chance to shock melee attackers Small amount of damage done to player 40% 004e400d
Empath Teammates take 25% less damage Player takes 33% more damage 004e1f16
Grounded Energy Resistance +100 Energy Damage -50% 004e4002
Healing Factor Health Regeneration while not in combat +300% Chem Effects -55% 004df1db
Herbivore Vegetables provides x2 benefit and no disease Eating meat doesn't satisfy hunger 003c404e
Herd Mentality All SPECIAL stats +2 when grouped All SPECIAL stats -2 when solo 004e1f1e
Marsupial Carry weight +20, +jump height INT -4 004df1ce
Plague Walker Poison aura scaling with your diseases Diseases 004e4021
Scaly Skin Damage and Energy Resistance +50 AP -50 004df1cf
Speed Demon Movement speed +20%, faster reload +20% +50% drain on hunger and thirst while moving 004df1e0
Talons Punching attacks do 25% more damage + bleed damage AGI -4 0028d3bc
Twisted Muscles Melee damage +25%, better chance to cripple limbs Gun accuracy -50% 003c402f
Unstable Isotope Medium chance to release a radiation blast when struck in melee. Minor damage to player during the radiation blast 10% 004e4017

Available serums

Mutation Serum Serum Recipe
Adrenal Reaction Adrenal reaction serum Recipe: Adrenal reaction serum
Bird Bones Bird bones serum Recipe: Bird bones serum
Carnivore Carnivore serum Recipe: Carnivore serum
Chameleon Chameleon serum Recipe: Chameleon serum
Eagle Eyes Eagle eyes serum Recipe: Eagle eyes serum
Egg Head Egg head serum Recipe: Egg head serum
Electrically Charged Electrically charged serum Recipe: Electrically charged serum
Empath Empath serum Recipe: Empath serum
Grounded Grounded serum Recipe: Grounded serum
Healing Factor Healing factor serum Recipe: Healing factor serum
Herbivore Herbivore serum Recipe: Herbivore serum
Herd Mentality Herd mentality serum Recipe: Herd mentality serum
Marsupial Marsupial serum Recipe: Marsupial serum
Plague Walker Plague walker serum Recipe: Plague walker serum
Scaly Skin Scaly skin serum Recipe: Scaly skin serum
Speed Demon Speed demon serum Recipe: Speed demon serum
Talons Talons serum Recipe: Talons serum
Twisted Muscles Twisted muscles serum Recipe: Twisted muscles serum
Unstable Isotope Unstable isotope serum Recipe: Unstable isotope serum


  • PCIcon pc Playstation 4Icon ps4 Xbox OneIcon xboxone The Class Freak perk card seems to have a bug on the effects page of the Pip-Boy, where it isn't showing any reduction to the Empath and Herd Mentality negative effects while it is for the other mutations. For the Herd Mentality it seems only a visual bug, the negative effect of having SPECIAL reduced by 2 when solo and in combination of rank 3 Class Freak doesn't reduce SPECIAL at all when equip. For the Empath negative effect, this is a confirmed bug, the +33% of damage to player is not reduced at all.[verified]
  • PCIcon pc Playstation 4Icon ps4 Xbox OneIcon xboxone Chameleon often glitches, and will render the character invisible from the player regardless of whether or not they're holding their weapon, wearing armor, or in motion. At times even just the character's exposed skin in rendered invisible, while their clothing remains visible.[verified]
  • PCIcon pc Playstation 4Icon ps4 Xbox OneIcon xboxone The Grounded mutation with the Class Freak perk (sometimes) says energy guns do 12% less damage (the correct amount) sometimes it says 50% less damage (the standard amount) but the energy gun damage is always 50% less.[verified]
  • PCIcon pc Playstation 4Icon ps4 Xbox OneIcon xboxone The Strange in Numbers perk can increase the effect of some mutations significantly. For example, combining it with the "Bird Bones" mutation can cause the player's fall speed to be reduced so much that it is possible to walk on air.[verified]
  • PCIcon pc Playstation 4Icon ps4 Xbox OneIcon xboxone The Herd Mentality mutation can prevent sharing of other perk cards with the group. This appears to be fixed in the December 11th patch[verified]
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