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For the condition that lists mutations, see mutations.
Each Disease has unique penalties. Use Disease Cures, Antibiotics, or wait until the Disease expires on its own.— In-game notification

Diseases are a type of condition in Fallout 76.

Causes and effectsEdit

Fo76 Disease icon

When the player character consumes unclean food and liquid, there is a chance of acquiring a disease. Being attacked by diseased creatures and sleeping on floor mattresses can also cause disease. Eating uncooked meat and drinking dirty water has the highest risks for disease.

Diseases cause a variety of effects including increased damage and needs, such as hunger.

PreventionEdit

Diseases can be avoided by cooking food, eating pre-War packaged food, and drinking boiled or purified water. Sleeping on raised mattresses and avoiding physical contact with diseased creatures will also avoid disease.

Maintaining a character's food and water needs each increases resistance of disease by 25%, even more (35%) with the perk Rejuvenated. Taking antibiotics also temporarily increases disease resistance, but using RadAway will temporarily reduce disease resistance by 50%. The perks Iron Stomach and Thirst Quencher greatly reduce the chance of disease from consumed food and liquid, respectively, while the perk Vaccinated protects against diseased creatures.

TreatmentEdit

Diseases are time-limited and will expire. They can be cured prior to their expiration with disease cures or antibiotics. Alternatively, drinking from a sulfur water fountain (one is located at a white gazebo near the Whitespring golf club) will cure a disease.

Intentional diseasesEdit

Intentionally catching diseases is useful with the Plague Walker mutation or attempting to complete the challenge for acquiring all diseases. Note that similar to mutations, diseases have a 30 minute cooldown for catching another disease, or 45 minutes for the same disease. Leaving the server resets this cooldown so that another disease can be immediately obtained upon joining a different server.

List of diseasesEdit

A player character can get infected by these diseases:

Disease Effect(s) Duration Base ID Cause
The Blight -1 to all S.P.E.C.I.A.L stats 30 min 004c6b3e Inflicted by a diseased Scorchbeast, Grafton monster, mega sloth, or mirelurk queen
Blood worms Take 25% more damage 15 min 003df043 Inflicted by a diseased radroach
Bone worms Take 50% more limb damage 15 min 00008881 Inflicted by a diseased mole rat or radrat, or stepping on traps such as a punji board
Buzz brain INT -2 60 min 004c6b34 Inflicted by a diseased ant
Dysentery Periodic water loss 15 min 00284956
0028495a
Eat raw carrots, spoiled meat, swim in toxic water
Fever claw -25% Damage with Ranged Weapons 15 min 004c6b48 Inflicted by a diseased mirelurk hunter
Flap limb STR -2 60 min 004c6b1f Inflicted by a diseased mirelurk
Glowing pustules Bleed radiation from wounds when hit 15 min 004b0095
004b0096
Inflicted by a diseased glowing one or radstag.
Heat flashes END -2 45 min 004c6b2a Inflicted by a diseased honey beast
Jelly fingers +50% Ranged VATS AP Cost 15 min 003c75c4 Inflicted by a diseased stingwing
Lock joint Melee AP cost +50% 15 min 003c75be Inflicted by a diseased wolf
Needle spine -10 Carry Capacity 15 min 003c75b8 Inflicted by a diseased angler.
Parasites Periodic food loss 15 min 00112e6d Inflicted by a diseased tick or bloodbug, swimming in water, eating raw mutfruit, drinking cream.
Rad worms Take 50% more radiation damage. 15 min 003df041 Inflicted by a diseased feral ghoul or a diseased mutant hound.
Rattle hands -25% damage with ranged weapons 45 min 004c6b4f Inflicted by a diseased mirelurk king
Shell shock Action Point drain from wounds 45 min 004b009c Inflicted by a diseased mongrel or deathclaw
Sludge lung Max AP -50, AP regen -50 60 min 0018ef92 Inflicted by a diseased wendigo, or exposure to toxic air without wearing a gas mask, assault gas mask, or spacesuit helmet
Snot ear PER -2 15 min 004c6b25 Inflicted by a diseased snallygaster or gulper
Swamp gas CHR -2 15 min 004c6b2f Inflicted by a diseased bloatfly
Swamp itch AGI -2 15 min 003cd03b Sleep in a sleeping bag/mattress on the ground.
Weeping sores Bleed from wounds 45 min 003df045
004a4a59
Inflicted by diseased radscorpions or yao guai
The Woopsies LCK -2 15 min 004c6b39 Inflicted by a diseased mirelurk spawn