A clever and loyal animal, Dogmeat is a skilled scavenger and a fierce fighter, skills that were not lost on his previous owner, who was killed by raiders in the vicinity of the Capital Wasteland scrapyard.[Non-canon 1] He has "good teeth and strong claws", according to the Lone Wanderer.
Dogmeat is found in the scrapyard, fighting off several raiders who killed the dog's prior owner. He may also be found fighting super mutants in a random place at The Mall. Regardless of any other companion or Karma level, Dogmeat can be recruited without incident.
If the event to encounter him is triggered and the Lone Wanderer does not approach him, he may wander off and be found elsewhere on the map.
Shooting Dogmeat in the initial encounter without talking to him will make it impossible to recruit him unless the Puppies! perk was taken.
Before the release of Fallout 3, the process of how to recruit Dogmeat had only been shown as a small clip as the Lone Wanderer holds something out to the wounded dog, although the item is never revealed. Dogmeat was initially to be found in a random encounter, appearing early on to help develop the Lone Wanderer's bond with the dog.
End of information based on Fallout 3 cut content.
His right eye is brown, while his left eye is blue, which is known as complete heterochromia.
In Little Lamplight, if Dogmeat is following you and you go into the testing chamber to explore, Dogmeat may appear dead while exiting. Then while leaving a room or house, Dogmeat's dead body will spawn outside next to where you entered. Dogmeat may or may not take up a character slot after dying this way. Dogmeat will also still be shown blinking. This also can happen to Jericho. [verified]
During the Blood Ties quest Dogmeat may disappear from the game after talking with Vance about making a deal with Arefu. Loading a previous save doesn't fix the bug. [verified]
The game might crash if you try to talk to Dogmeat while the battle is still ongoing in the Scrapyard. [verified]
Through the use of the Paralyzing Palm perk (or any weapon with a knockdown effect), Dogmeat can store items whose weight total exceeds 10,000 lbs. However, asking him to fetch you an item at any time will return all stored items. If you ask Dogmeat to return to Vault 101, you can pickpocket him and store items too. [verified]
Dogmeat's Inventory can be accessed any time after he has been told to "Go wait by Vault 101," simply by a standard pickpocket maneuver. The game will treat Dogmeat the same as any NPC whom is pickpocketed, so the player character can be caught. This will temporarily block from re-attempting accessing his inventory but can be completely avoided by saving and reverting. This may result in a karma loss. [verification overdue]
Despite being sent back to Vault 101, Dogmeat has shown up inside of the West residence in Arefu. After going outside, Dogmeat does not follow. [verified]
Attacking Dogmeat until he becomes hostile and then putting away your weapons will result in Dogmeat walking back to Vault 101. [verified]
After leaving Vault 101 for the first time, Dogmeat can be found outside, sometimes clipping into the ground. If interacted with, no dialogue options will appear and will not be recruitable as a companion, even if the player goes to the scrapyard. [verified]
If the player character kills an enemy while Dogmeat is attacking them, he will not notice that the enemy is already dead and keep attacking the corpse even past it being mutilated. [verified]
Dogmeat can be brought to Point Lookout by having him search for an item just before sleeping on the cot in the Duchess Gambit. He will approach the player in Point Lookout after six days. He can be returned to the Capital Wasteland simply by taking the Duchess back, resulting in him automatically waiting at Vault 101. This may not work until Nadine has control of the Duchess. [verified]