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This is an overview article which contains background information and cross-game comparisons. For game-specific information and stats, see the articles linked on the right.
Gameplay articles
Fallout 4Calmex
Calmex Silk Gametitle-FO4 NW
Fallout 76Calmex
Fallout: The Board GameCalmex
Gametitle-FO4Gametitle-FO4 NWGametitle-FO76Gametitle-FBG
Gametitle-FO4Gametitle-FO4 NWGametitle-FO76Gametitle-FBG

Calmex is a pre-War light tranquilizer. While it doesn't work as a pain killer when administered, it carries a high enough dosage to cause a boost to some survival senses that are ordinarily dulled by reasoning.



Fo4 Med-X
Gameplay articles: Fallout 4, Fallout 76

The standard variant. When used it boosts the user's Agility and Perception by 3, while also increasing sneak attack damage.

Calmex SilkEdit

Fo4 Med-X
Gameplay article: Nuka-World

A variant of Calmex produced by Maddox in the Nuka-Town market from bloodworm meat. While it is identical in appearance to standard Calmex, it boosts the user's Luck by 3 in addition to its usual effects.

Canonbox defaultThe following is based on content from Fallout: The Board Game and has not been confirmed by canon sources.

Calmex (Fallout: The Board Game)Edit

FBG calmex
Gameplay article: Fallout: The Board Game

Due to how gameplay works in Fallout: The Board Game, Calmex has different effects and usage than in other games. Rather than boosting multiple SPECIAL stats and sneak attack damage, Calmex can be used during a fight or test to automatically gain either one point of agility or perception. After this, the player character must pass an endurance check or gain the addicted trait.

Canonbox defaultEnd of information based on content from Fallout: The Board Game.
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