The company was founded in 2071 by Nina Valaya, a former scientist at Oressa Polytechnic and researcher at West Tek. Valaya was known for "flexible ethical standards" and wrote over 55 papers on cross-species genetics. The company also employed microbiologist Molly Cooper, who developed a close relationship with Valaya. Both of them were later accepted as part of the scientific research team in Vault 96.
CHROMAX Genetics is mentioned only in Fallout 76.