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For the Buffout that appears in the Fallout series, see Buffout.
Buffout is a powerful steroid that gained popularity with athletes before the Great War. It grants temporary bonuses to Strength, Endurance and maximum Health.— Loading screen hint

Buffout is a consumable item in Fallout 4.


The addiction effects are -1 Strength and -1 Endurance once Buffout has worn off. It appears as a small brown jar with a white lid, presumably holding pills of Buffout inside of it.

Variants Edit


Due to being a chem, when survival mode is active, it will increase thirst by 22.5 points and raise the disease risk by 7% at the next disease check.



  • At the E3 showcase, it is in the Sole Survivor's inventory when they obtained their Pip-Boy.[1]
  • It is the only major chem that cannot be made at a chemistry station.



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