This is an overview article which contains background information and cross-game comparisons. For game-specific information and stats, see the articles linked on the right.
Buffout is a highly potent anabolic steroid that was popularized before the Great War by professional athletes and their clandestine use of the drug. Using too much Buffout causes cardiac arrest, possibly leading to death.
The pill-shaped drug, typically contained in small bottles, increases
strength and reflexes, with the disadvantage of being highly addictive. Buffout is similar to real life steroids.
Buffjet: Introduced in , this variant is made in a Fallout 4 chemistry station and is a combination of Buffout and Jet. Effect: Slows time for 15 seconds.
Psychobuff: Another Buffout variant introduced in Fallout 4. Made in a chemistry station using Psycho and Buffout. Effect: +25% damage dealt, +3 Strength, and +3 Endurance.
Bufftats: Another Buffout variant introduced in Fallout 4, this variant is made in a chemistry station using Buffout and Mentats. Effect: +3 Strength, +3 Endurance, +65 HP, and +3 Perception.