|The following is based on Fallout Tactics and is not canon.|
Brimstone Squad is the best of the best. They're comprised of eight highly seasoned and battle-hardened Brotherhood Paladins, and the high general of the Brotherhood himself. However, that didn't stop them from being slaughtered by the mutant ambush in St. Louis, where the mutant armies killed them and abducted the high general. The only surviving member was Burke.
Interactions with the player character
The Warrior interacts with the squad's leader, General Barnaky, throughout the game. During the mission in St. Louis, the player will happen upon the last survivor of the ill-fated Brimstone Squad, Burke.
Brimstone Squad only appears in Fallout Tactics.