Many of Boston's famous monuments such as The Paul Revere Monument, the Massachusetts State House with its unique golden dome, the USS Constitution, Scollay Square, the Bunker Hill memorial and Fenway Park still stand after the Great War.
Boston was founded by European colonists in 1630. Many important historical events of the American Revolution, such as the Boston Massacre, the Boston Tea Party, Paul Revere's midnight ride, the Battles of Lexington and Concord and the Battle of Bunker Hill occurred in or near Boston. Boston was located within Suffolk County.
As the Resource Wars continued, the food supply started to dwindle. Rationing sites were set up around Boston, including the Boston Police rationing site. In October 2077, an unknown person smashed the glass of the Roxbury Food Bank. Soldiers opened fire on civilians, with at least four confirmed dead and eight injured. Food riots started over the city, like in Denver.
The Institute, previously known as the Commonwealth Institute of Technology, or CIT was a prestigious university located in Boston. Robert House was believed to be an alumnus pre-War. During the Great War, a number of CIT personnel survived by taking refuge in the underground level of the campus. In 2110, the survivors and their descendants founded the Institute, an organization dedicated to furthering pre-War science. The scientific community inhabiting the university-created technologies vastly superior to anything else seen in the wasteland. Androids or "synths," specifically, are one of the creations to come out of the Institute.
Boston itself was never hit directly; instead, an area southwest of the city was targeted, mainly due to the industrial and military significance it held. Despite this, Boston's status as a major city would suggest that it was attacked in some form. Only one bomb hit the Greater Boston area during the Great War, and Bonnie's holotape, Log - SSG Michael Daly and the Backyard bunker terminal entries imply that most of Boston survived the nuclear exchange. In the following weeks, fighting was reported within the city. At some point, local military forces seized locations like the Mass Bay Medical Center but were soon overwhelmed, causing society to finally collapse.
By the 23rd century, the ground zero and outlying areas of the region became known as the Glowing Sea. Even 210 years later, the area remained dangerously irradiated, periodically stirring up radiation storms which would breach the confines of the Glowing Sea and threatened the entire Boston region.
Post-War, the Commonwealth has been described by Dr. Zimmer as "a war-ravaged quagmire of violence and despair." However, the Commonwealth (which includes Boston) seems to be one of less devastated areas in the post-War USA, so Zimmer's impression seems to be primarily based on the fact that he likely grew up inside the Institute, where the standard of living is much higher.
The city center is composed of several tall skyscrapers though they have been worn with time. As of 2287, many pre-War buildings, monuments, and landmarks still stand. Some have been renovated with scavenged parts, their ramshackle appearance suggesting that central Boston may have partly tried to defend themselves against a nuclear attack in some way, as Robert House did with Las Vegas.
The areas outside the city center are rolling barren plains, wastelands, swamps and what's left of suburbs. To the southwest of the map, there is a growing appearance of radiation leading to the Glowing Sea. The terrain is bumpy and is scattered with pockets of high and low radiation levels. Small collectives of irradiated water scatter the area. Information in the game indicates a high-yield nuclear warhead detonated to the southwest of Boston. This is supported by the Pip-Boy map, which shows part of a circle at the bottom left which appears to be the crater the nuclear warhead created. As to if Boston was the intended target or not remains unknown.
The city's skyscrapers make Boston viewable from most locations on the map.